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IMGD: an integrated platform supporting comparative genomics and phylogenetics of insect mitochondrial genomes
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 Authours
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Wonhoon Lee*, Jongsun Park*, Jaeyoung Choi, Kyongyong Jung,
Bongsoo Park, Donghan Kim, Jaeyoung Lee, Kyohun Ahn, Wonho Song,
Seogchan Kang, Yong-Hwan LeeĦ× and Seunghwan LeeĦ× |
| Title |
IMGD: an integrated platform supporting comparative genomics and phylogenetics of insect mitochondrial genomes |
| Journal |
BMC Genomics, 2009 (10) ~ |
Abstract
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Background
Sequences and organization of the mitochondrial genome have been used as markers
to investigate evolutionary history and relationships in many taxonomic groups. The
rapidly increasing mitochondrial genome sequences from diverse insects provide
ample opportunities to explore various global evolutionary questions in the superclass
Hexapoda. To adequately support such questions, it is imperative to establish an
informatics platform that facilitates the retrieval and utilization of available
mitochondrial genome sequence data.
Results
The Insect Mitochondrial Genome Database (IMGD) is a new integrated platform that
archives the mitochondrial genome sequences from 25,747 hexapod species, including
112 completely sequenced and 20 nearly completed genomes and 113,985 partially
sequenced mitochondrial genomes. The Species-driven User Interface (SUI) of IMGD
supports data retrieval and diverse analyses at multi-taxon levels. The Phyloviewer
implemented in IMGD provides three methods for drawing phylogenetic trees and
displays the resulting trees on the web. The SNP database incorporated to IMGD
presents the distribution of SNPs and INDELs in the mitochondrial genomes of
multiple isolates within eight species. A newly developed comparative SNU Genome
Browser supports the graphical presentation and interactive interface for the identified
SNPs/INDELs.
Conclusion
The IMGD provides a solid foundation for the comparative mitochondrial genomics
and phylogenetics of insects. All data and functions described here are available at the
web site http://www.imgd.org/. |
Link
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