| |
|
|
| |
|
|
Research  |
|
|
|
| |
| |
TGFam‐Finder : a novel solution for target‐gene family annotation in plants
|
|
|
|
|
|
| |
|
 Authours
|
Seungill Kim*, Kyeongchae Cheong*, Jieun Park, Myung-Shin Kim, Jihyun Kim,
Min-Ki Seo, Geun Young Chae, Min Jeong Jang, Hyunggon Mang, Sun-Ho Kwon,
Yong-Min Kim, Namjin Koo, Cheol Woo Min, Kwang-Soo Kim, Nuri Oh, Ki-Tae Kim,
Jongbum Jeon, Hyunbin Kim, Yoon-Young Lee, Kee Hoon Sohn, Honour C. McCann,
Sang-Kyu Ye, Sun Tae Kim, Kyung-Soon Park, Yong-Hwan Lee and Doil Choi |
| Title |
TGFam‐Finder : a novel solution for target‐gene family annotation in plants |
| Journal |
NEW PHYTOLOGIST, 2020 (227) ~ |
Abstract
|
- Whole-genome annotation error that omits essential protein-coding genes hinders further
research.
- We developed Target Gene Family Finder (TGFAM-FINDER), an alternative tool for the structural annotation of protein-coding genes containing target domain(s) of interest in plant genomes. TGFAM-FINDER took considerably reduced annotation run-time and improved accuracy compared to conventional annotation tools.
- Large-scale re-annotation of 50 plant genomes identified an average of 150, 166 and 86
additional far-red-impaired response 1, nucleotide-binding and leucine-rich-repeat, and
cytochrome P450 genes, respectively, that were missed in previous annotations. We detected significantly higher number of translated genes in the new annotations using mass spectrometry data from seven plant species compared to previous annotations.
- TGFAM-FINDER along with the new gene models can provide an optimized platform for comprehensive functional, comparative, and evolutionary studies in plants. |
Link
|
 |
|
|
| |
|
|
|
|
| |
|
|
|
|
